What exactly is Methyl Salicylate?

Therefore, What Exactly Is Methyl Salicylate? A Close In Accordance With Menthol

Methyl salicylate is a normal ester that executes very much like menthol. It really is commonly removed through vapor distillation of wintergreen leaves.

Based on WebMD, methyl salicylate can be found in numerous topical creams purchased throughout the countertop for minor joint aches or muscular discomforts. It may also be present in intimate items.

Therefore, what exactly is methyl salicylate and what does it do? Both menthol and methyl salicylate are referred to as counterirritants, meaning they cause cooling and warming feelings on your skin. Counterirritants are primarily accountable for the title, and effect, known as “icy hot.”

Many of these services and products shouldn’t be utilized on younger kids as a result of poisoning issues, which we’ll speak about later in this specific article.

Wintergreen Oil

You might nevertheless be wondering, what exactly is methyl salicylate? You shall usually hear about wintergreen“oil or oil of wintergreen.” Relating to an overview in the Journal of Alternative Complementary Medicine, methyl salicylate could be thepredominant ingredient within the oil and is particularly the purest kind in the greatest concentration you certainly will find. Based on an oil wintergreen podcast through the Royal community of Chemistry, oil of wintergreen contains 96-99% methyl salicylate. Through the same supply, “…research has shown that methyl salicylate is a component of a plant’s toolbox within the battle against pathogens and herbivores.”

Methyl salicylate smells extremely highly of mint. Notwithstanding this, it will additionally be noted that this ingredient will not belong within the mint genus of plant species. The burning sensation that is cold activated through the TRPA1 channel. Methyl salicylate additionally activates the warmth channel TRPV1, which can be exactly the same channel regarded as triggered by chilli peppers like capsaicin. Often, wintergreen oil is employed along with peppermint oil, considering that the two in tandem are thought to attenuate effects that are beneficial. Wintergreen oil is acquired by vapor distillation of this warmed, water-macerated leaves. It really is often utilized interchangeably with sweet birch oil for flavoring meals and sweets.

Particular Products Which Use Methyl Salicylate

Based on drugs.com and goodguide.com, you’ll find so many products which have methyl salicylate. Some items include…


Icy Hot Cream

Salonpas Pain Patch

Analgesic Balm



Menthocin Patch with Lidocaine

Soothee Patch




CVS Mouth Rinse Natural Citrus

CVS Antiseptic Mouth Rinse

K-Y Yours+Mine Partners Lubricant

Jason Natural Cosmetics Dandruff Relief Treatment Shampoo

Forever Living Aloe Heat Lotion

Colgate Peroxyl Antiseptic Oral Cleanser, Original

Orajel PM Toothache cream

CVS Excessive Strength Toothache relief

Young Residing Thieves Dentarome Ultra Toothpaste

Eco-Dent Specialcare Toothpowders Tartarguard

Comparing Methyl Salicylate to Aspirin

One research published in the Annals of Pharmacotherapy aimed to analyze the effectiveness of methyl salicylate in platelet inhibition when comparing to aspirin. Platelet aggregation is another means of referring to platelets clumping together into the bloodstream. This is certainly associated with blood clotting.

This research utilized a tiny sample of nine healthier males into the 30-46 a long time. All individuals were given 162 mg of aspirin before a washout period and then 5 g of 30% methyl preparation that is salicylate both to be utilized on the anterior thighs. It had been discovered that “both aspirin and MS produced statistically significant platelet inhibition; aspirin decreased the AUC from 183; 139 to 292 to 85; 48 to 128 (p = 0.008) and MS decreased the AUC from 197; 118 to 445 to 112; 88 to 306 (p = 0.011).”

There clearly was no difference that is large the 2. This implies that methyl salicylate works because effortlessly as aspirin for platelet aggregation, at least in healthier people.

Poisoning Fables and Concerns

Research with this substance on the web will reveal a number of instance reports of baby death. a things that are few be noted about these. Such baby fatalities frequently included the accidental swallowing of pure oil of wintergreen, the greatest concentration of methyl salicylate you will get.

This does not imply that overdoses is only able to take place with ingestion; the substance could be absorbed through your skin then incorporated into one’s system. But, it absolutely was present in “Toxicity urban myths: the risk that is actual of Acrylic Use,” published into the Global Journal of Aromatherapy, that, “if 10?ml of a 2.5% formula of wintergreen oil had been to be reproduced all at the same time towards the skin and completely absorbed, the dose would represent the exact same level of salicylate present in one single 325?mg aspirin tablet.”

For this reason oil of wintergreen is known as to be reasonably low-risk with few effects that are side. But, it is suggested that brand brand new moms and dads avoid obtaining the substance in the homely household, from the off-chance that a baby could easily get their or her fingers upon it.

Also, it really is well worth noting that methyl salicylate happens to be limited for usage in cosmetics in Canada.

Trace Quantities Are Contained In Hemp Seed Oil

Among numerous health great things about hemp seed oil constituents, you could find trace amounts of methyl salicylate. Hemp seed oil’s fatty acid content (omega-3s and omega-6s) is most memorable as a plus that is nutritional. The oil also contains 10-15% dietary fiber, 20-25% protein, and 20-30% carbs.

A bioassay posted in “The structure of Hemp Seed Oil and Its Potentialas a source that is important of” reported from the methyl salicylate content of hemp seed oil. Additionally they reported on the other side things contained in hemp seed oil, such as for instance cannabidiol, ?-Sitosterol, tocopherols, and terpenes and terpenoids.

In Closing

Therefore let’s go over what we’ve learned therefore far:

Methyl salicylate is really an ester that is natural could be made organically or synthetically within the lab it is frequently removed via vapor distillation of wintergreen leaves.

Oil of wintergreen may read this article be the strongest, purest concentration of methyl salicylate.

USUALLY DO NOT INGEST oil of wintergreen.

Methyl salicylate can be present in over-the-counter services and products such as for instance toothache creams and muscle mass pain relievers to alleviate discomfort and result in a soothing feeling. Additionally it is often utilized in a small amount to taste meals and sweets.

Wintergreen oil placed on skin when you look at the doses that are right express the exact same quantity of salicylate present in one 325 mg aspirin tablet.

Methyl salicylate works effortlessly against platelet aggregation—about as much as aspirin does.

Methyl salicylate can be found in hemp seed oil in trace quantities.